Officials informed news outlets that the province of Balochistan was attacked early on Thursday.
According to authorities, the death toll might rise, as many people were killed when buildings fell.
According to the Reuters news agency, many of the victims were women and children.
According to the US Geological Survey, the quake had a magnitude of 5.9 and occurred at a shallow depth of 9 kilometers. Shallow quakes have the potential to do more harm.
At least 150 people are believed to have been hurt, according to local officials, with some of them taken to hospitals in severe condition.
Military physicians and paramedics have reportedly arrived in earthquake-stricken areas to aid with relief efforts, according to local media.
Pakistan army helicopters airlifted a number of severely injured persons to Quetta, the provincial capital.
According to Reuters, several patients were treated on stretchers with doctors using phones as flashlights.
Hundreds of people have been displaced as more than 100 mud dwellings collapsed and a huge number of structures were destroyed, according to an official.
“I have ordered urgent help on an emergency basis for the Harnai, Balochistan, earthquake victims & for a quick assessment of the damage for prompt relief & compensation,” Prime Minister Imran Khan wrote on Twitter.
According to authorities, the Harnai district looks to have taken the brunt of the devastation.
Harnai, east of Quetta, contains a high number of coal mines that might collapse after an earthquake.
Emergency services have been deployed to the region, according to Balochistan’s interior minister, Mir Ziaullah Langu.